General Cell Lines and Cell Cultures
iXCells Biotechnologies Human Intestinal Microvascular
Human Intestinal Microvascular Endothelial Cells (HIMEC)
Medchemexpress LLC CD47 protein, rat (HEK293, Fc) | 95.0% | 100 UG
Recombinant rat CD47 (leukocyte surface antigen) produced in HEK293 cells with a C-terminal human Fc fusion. Supplied as 100 μg for research applications; store at -20°C and ship on blue ice. Protein accession P97829 and gene ID 29364 are provided where available.
Amsbio LLC HCT-116 Wnt reporter stable cell Line (Mutant)
HCT-116 Wnt reporter stable cell Line (Mutant)
Lonza Walkersville D-HAEC - Diabetes Type II
Diseased Human Aortic Endothelial Cells are isolated from human donors that have been diagnosed with diabetes type I or type II disease Diseased cells are grown in the same optimized media system as Normal Human Endothelial Cells Diabetic cultures can be used for experimental applications in diabetic-related cardiovascular pharmaceutical development vascular pathology including atherosclerosis Cryopreserved Clonetics Diabetic Human Aortic Endothelial Cells are shipped in third passage Proliferating Clonetics cells are shipped in fourth passage All cells test negative for mycoplasma bacteria yeast and fungi HIV-1 hepatitis B and hepatitis C are not detected for all donors and/or cell lots A Certificate of Analysis is provided for each cell lot purchased
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Trachea, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx Ready-to-Assay NMU1 Neuromedin U Receptor Frozen Cells, 2 Vials of Cells. (HTS062RTA)
The Ready-to-Assay nMU1 Neuromedin U Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. Neuromedin U) based activation of nMU1R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses nMU1R alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of nMU1R, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter CXCR6 Total Internalization U2OS Cell Line, 2 vials. (93-0886C3)
The PathHunter CXCR6 Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CXCR6 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged CXCR6 and a ProLink-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CXCR6 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Spleen, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter CHO-K1 GPR148 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0364C2A)
The PathHunter GPR148 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR148 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR148 and EA-tagged β-Arrestin-2. Activation of GPR148 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC COLO205 FFPE Cell Pellet Slide (5-pack)
FFPE cell line sections are manufactured using a proprietary technology that maintains both cell morphology and preserves nucleic acids and proteins. Available from over 120 tumor cell lines, these FFPE sections make for affordable and consistent controls without compromising quality or consistency. Using cell line controls overcomes issues experienced with traditional cell or tissue-based control specimens such as intra specimen variation, lot-to-lot variations and inconsistent biomolecule quality. Also available in scroll & block formats - please enquire.
Biochain Institute Inc Paraffin Tissue Section Panel - Human Tumor, Same Tumor Type, Different Donors (5 tissues), 5 slides/PK
BioChain's FFPE multiple tissue panels from the same type of tumors are designed for rapidly screening expression of tumor specific genes or proteins. Tumor tissue sections with the same tissue type collected from three different donors are arrayed along with a corresponding normal control tissue section on positively charged glass slides. Documentation of tissues' clinical histories may be available upon request. Human placenta tissue section is included in each panel as an interpanel control for comparison between different tissue panels. he tissue sections are approximately 5-10 um thick.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Tonsilla Cerebelli, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter THP-1 IκB Degradation Cell Line, 2 vials. (93-0538C14)
The PathHunter THP-1 IκB Degradation Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the NFκB pathway. This cell line enables detection of IκB levels, allowing for assessment of NFκB pathway activation-induced IκB degradation. This product uses EFC technology. The cell line included overexpresses IκB target protein fused to ProLabel. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of IκB EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Eurofins Discoverx InCELL Hunter A549 PRMT3 Methyltransferase Cell Line, 2 vials. (96-0072C15)
The InCELL Hunter A549 PRMT3 Methyltransferase Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with regulators of epigenetics pathways. This cell line enables assessment of compound-engagement-based stabilization of PRMT3 via detection of PRMT3 levels. This product uses EFC technology. The cell line included overexpresses PRMT3 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/epigenetics.